IndraLab

Statements

USP39 inhibits SNRNP200. 3 / 3
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"In the splicing reaction, on the other hand, Sad1 could potentially directly or indirectly suppress the activity of Brr2."
29330354
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"In contrast, human Brr2 is held in an unengaged position in the tri-snRNP by Sad1, which may repress premature Brr2 unwinding of U4/U6 interactions [ 5 •• ] ( Figure 1 )."
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"In the human tri-snRNP assembly, SNRNP200 is sequestered by hSad1 ( USP39 ) in a preactivation position close to Prpf8 RT domain and Prpf6 [21] ."
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