IndraLab

Statements


CYLD activates TCR. 2 / 2
| 2

reach
"We have previously shown that CYLD positively regulates LCK function and TCR proximal signaling in thymocytes."

reach
"Mechanistic studies reveal that CYLD positively regulates TCR signaling in thymic DP cells through binding and removing K63- and K48-linked ubiquitin chains from active LCK, facilitating LCK recruitment of ZAP70 and promoting thymocyte development (61)."