IndraLab

Statements

OTUD5 deubiquitinates RNF186. 2 / 2

| 2

reach

"OTUD5 can activate the mTOR signalling pathway by deubiquitinating ring finger protein 186 (RNF186), thereby promoting the progression of bladder cancer [10]."

38658981

➶

reach

"The specific mechanism is that OTUD5 deubiquitinates RNF186 and stabilizes its protein levels, which, in turn, leads to the increased degradation of Sestrin2 and the subsequent activation of the mTOR pathway [11]."

37190070

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

OTUD5 deubiquitinates RNF186. 2 / 2

INDRA sources:

Databases

Reading