IndraLab

Statements

USP25 activates IFNB1. 3 / 3
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"Consistently, Usp21 deficiency resulted in production of more IFNbeta and TNF in MEFs and BMDMs in response to HSV-1 infection (XREF_FIG)."
28254948
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"Notably, Usp21 fl/fl Lyz2-cre mice produced significantly higher concentrations of IFNbeta, IL-6, and TNF in serum upon HSV-1 infection compared with infected control mice (XREF_FIG)."
28254948
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"Furthermore, Knockdown of USP25 potentiated virus induced induction of the IFN-beta."
24260525