IndraLab

Statements

USP1 inhibits Ubiquitin. 4 / 6
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"However, a structural relationship to ubiquitin has been recently proposed for human USP1, which is inactivated by auto‐cleavage after an internal ubiquitin‐like di‐glycine motif."
17597129
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"In the past year, two other deubiquitinating enzymes, USP27X and USP1, have been reported to impede ubiquitin mediated degradation of Snail1 in various biological contexts XREF_BIBR, XREF_BIBR."
33391500
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"We therefore reasoned that pharmacologic inhibition of USP1 would promote ubiquitin mediated degradation of ID1 protein, resulting in differentiation and growth inhibition of immature leukemic cells."
24130053
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"Wild-type USP1, but not USP1 C90S, reduced the amount of ID2 modified with HA tagged ubiquitin."
21925315