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USP48 activates Genomic Instability. 2 / 2

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"We propose that USP48 promotes genome stability by antagonizing BRCA1 E3 ligase function."

29335415

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"Importantly, the results of the present study show that loss of USP48 improves DNA repair and prevents genomic instability of FA defective cells, thus highlighting the potential of developing USP48 inhibitory molecules as novel therapeutic approaches that could potentially alleviate the phenotypes of FA patients."

29891926

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IndraLab

Statements

USP48 activates Genomic Instability. 2 / 2

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