IndraLab

Statements

CDK1 inhibits USP7. 3 / 3
| 3
reach
"Our work reveals that USP7 limits CDK1 activity at all cell cycle stages, providing a novel mechanism that explains the toxicity of USP7 inhibitors through untimely activation of CDK1."
33856059
reach
"This site is phosphorylated by the M-phase-specific kinase CDK1/cyclin B, thereby preventing UHRF1 from binding to a deubiquitinase Ubiquitin-specific protease 7(USP7), and reducing the protein stability of UHRF1 during M-phase of cell cycle (Fig. 1)."
38725075
reach
"USP7 limits CDK1 activity throughout the cell cycle."
33856059