IndraLab

Statements

BIRC5 binds USP19. 17 / 17
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"To assess the mechanism of this possible interaction between USP19 and survivin, we next treated HCC827 cells with MK2206, an AKT activity inhibitor, finding that the binding of USP19 to survivin was [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Survivin T34A mutant impaired the binding of USP19 to survivin in the presence of gastrodin ( Fig. 4 G)."
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"These data suggest that gastrodin induces NSCLC apoptosis by interfering with the binding of USP19 to Survivin Thr34."
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"Our present study found that gastrodin treatment interfered with USP19 binding to survivin, promoting survivin ubiquitination and apoptosis."
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"Moreover, gastrodin can inhibit the interaction between USP19 and survivin to stimulate the destruction and ubiquitination of survivin."
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"This observation supported the notion that gastrodin-induced apoptosis in NSCLC cells by interfering with the binding of USP19 to survivin."
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"To assess the mechanism of this possible interaction between USP19 and survivin, we next treated HCC827 cells with MK2206, an AKT activity inhibitor, finding that the binding of USP19 to survivin was [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Survivin T34A mutant impaired the binding of USP19 to survivin in the presence of gastrodin ( Fig. 4 G)."
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"These data suggest that gastrodin induces NSCLC apoptosis by interfering with the binding of USP19 to Survivin Thr34.We next established the xenograft mouse model to study the possible anti-neoplastic[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Our present study found that gastrodin treatment interfered with USP19 binding to survivin, promoting survivin ubiquitination and apoptosis."
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"Moreover, gastrodin can inhibit the interaction between USP19 and survivin to stimulate the destruction and ubiquitination of survivin."
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No evidence text available
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"Therefore, we first verified the potential effects of gastrodin on the interaction between USP19 and survivin in A549 cells."
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"Co-immunoprecipitation assay results suggest that gastrodin impaired the interaction between USP19 and survivin ( Fig. 4 A )."
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"This observation supported the notion that gastrodin-induced apoptosis in NSCLC cells by interfering with the binding of USP19 to survivin."
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