IndraLab

Statements


SCN8A decreases the amount of IL6. 5 / 5
| 5

reach
"XREF_FIG, MED suppressed the protein levels of TNF-alpha, IL-6, and IL-1beta in plasma and the mRNA levels of TNF-alpha, IL-6, and IL-1beta in the aortic arch."

reach
"Consistently, MED significantly suppressed the levels of serum IL-1beta and IL-6 (XREF_FIG)."

reach
"Furthermore, MED could significantly suppress the mRNA levels of TNF-alpha, IL-1beta and IL-6 induced by LPS (XREF_FIG), indicating that MED inhibits LPS induced cytokine expression at the transcriptional level."

reach
"Herein, we have shown that MED can significantly inhibit the ox-LDL-induced expression of TNF-alpha, IL-6, and IL-1beta both in RAW264.7 cells and in plaque lesion areas, which suggests that MED can suppress inflammatory responses in atherosclerosis."

reach
"The MED feeding significantly downregulated the expressions of the p50, p65, TNFalpha, IL-6, IFNalpha, IFNbeta, IL-12-p40, and CXCL2 genes compared to the ED mice (XREF_FIG)."