IndraLab

Statements

LMP1 increases the amount of UCHL1. 7 / 7
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"EBV LMP1 induces the expression of UCH-L1."
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"However, because LMP1 levels are low in dually infected PEL cells, and knockdown of LMP1 did not completely abrogate the increase in uch-l1 expression observed in BC-1 cells compared to BC-3 cells, these findings can not eliminate the possibility that EBNA1 or EBV encoded non polyadenylated RNAs (EBER1 and EBER2) contribute to the up-regulation of uch-l1."
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"KSHV LANA and EBV LMP1 together induce the expression of UCH-L1."
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"LMP1 also induced the expression of UCH-L1 in a dosedependent manner (XREF_FIG)."
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"Results showed that LMP1 was sufficient to induce uch-l1 expression, and co-expression of LMP1 and LANA had an additive effect on uch-l1 expression."
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"KSHV LANA and EBV LMP1 induce the expression of UCH-L1 following viral transformation."
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"These data indicate that EBV LMP1 can induce the UCHL1 endogenous expression in cells by activating its promoter."
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