IndraLab

Statements


OTUD5 activates mTORC1. 2 / 2
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"Prior research has demonstrated that OTUD5 modulates mTORC1 activity by destabilizing its inhibitory core proteins ."

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"In bladder cancer, OTUD5 activates mechanistic target of rapamycin complex 1 (mTORC1) signalling by deubiquitinating and stabilizing ring finger protein 186 (RNF186) and promoting sestrin2 degradation [10]."