IndraLab

Statements

CD274 binds RGMB. 5 / 5
| 5
reach
"XREF_BIBR PD-1 binds programmed death ligand 1 and 2, while PD-L1 also interacts with CD80 and PD-L2 interacts with RGMb (repulsive guidance molecule B)."
28761757
reach
"PD-L1 also binds to CD80, whereas PD-L2 uses repulsive guidance molecule (RGM) domain family member B (RGMB) as an alternative binding partner."
31888191
reach
"PD-1 inhibitors block the interaction between PD-1 and B7.1/PD-L1, while PD-L1 inhibitors block the interaction between PD-L1 and PD-1 and RGMB."
33585195
reach
"In contrast, PD-L1 and PD-L2 can exert inhibitory function independent of PD-1 by binding to B7-1 (CD80) and RGMb, respectively."
29255458
reach
"PD-L1 and PD-L2 share PD-1 as a binding partner, but PD-L2 can also bind RGMb."
37138075