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USP6 deubiquitinates GOLPH3. 2 / 2
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"In this article, we affirmed that USP6 was directly responsible for the deubiquitination of GOLPH3 protein and acted as an oncoprotein in COAD."

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"By deubiquitinating GOLPH3, Overexpression of USP6 increased the viability of COAD cells, prevented apoptosis, and sped up the growth of transplanted tumors both in vivo and in vitro."