IndraLab

Statements

DNAJA2 inhibits KCNH2. 2 / 2
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"Our observations are thus similar to those described by Walker and colleagues, who reported that DnaJA1, DnaJA2 and DnaJA4 reduced hERG channel maturation, whereas over-expression of Hsc70 alone had no effect on maturation events XREF_BIBR."
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"Knockdown of DNAJA1, but not DNAJA2 or DNAJA4, also reduces Kv11.1 maturation [88], perhaps consistent with the roles of chaperones as both pro-degradation and pro-folding factors [89]."
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