IndraLab

Statements

CYLD activates ERK. 6 / 6
| 5 1
reach
"57 They reported that in human lung A549 cells and lungs of Cyld -/- mice, CYLD targets the activation of ERK."
28372529
reach
"However, because Cyld deficiency did not cause the activation of ERK, the target of CYLD might be an intermediate signaling factor specifically mediating the activation of JNK and IKKbeta."
17548520
reach
"The finding that CYLD may target the ERK pathway in negatively controlling IL-8 expression is particularly significant."
25389768
reach
"However, it remained largely unknown whether or how CYLD modulated ERK signaling, when induced by bacterial pathogens."
25389768
reach
"Here, we examine both human lung epithelial A549 cells and lung of Cyld -/- mice to show that CYLD specifically targets the activation of ERK."
25389768
sparser
"Autophagy is an intrinsic defense mechanism against Lm and, therefore, we further investigated whether CYLD-dependent RIPK2 and ERK1/2 activation influences the formation of autophagosomes."
26834734