IndraLab

Statements

USP14 activates CREBBP. 3 / 3
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"Furthermore, we revealed a previously uncharacterized biological function of USP14 : Inhibition of USP14 reduced the stability of CBP, thereby lessening the severity of pathogen induced lung inflammation."
28611184
reach
"We found that the DUB USP14 targeted CBP for deubiquitylation, resulting in stabilization of CBP."
28611184
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"USP14 stabilizes CBP by diminishing its ubiquitination, whereas inhibiting USP14 deregulates the abundance of CBP and prevents LPS-mediated cytokine release."
35069211