IndraLab

Statements

MYSM1 binds TRAF3. 3 / 3
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sparser
"Notably, TRAF2 and TRAF3—key adapters in NF-κB signaling and known to form functional complexes—were among the top hits, consistent with prior reports of MYSM1–TRAF3 or MYSM1–TRAF6 interactions xref – xref ."
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sparser
"Reciprocal knockdowns demonstrated that TRAF2 depletion diminished MYSM1–TRAF3 binding, and TRAF3 depletion diminished MYSM1–TRAF2 binding (Fig. xref ), suggesting that MYSM1 engages each protein in a non–mutually exclusive manner."
41162619
reach
"Cytoplasmic MYSM1 associated with K63- and K48- linked polyubiquitins, TRAF3 and TRAF6, but not pCAF ( Figure 4 G)."
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