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JOSD2-LKB1 inhibits JOSD2. 1 / 1
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"The therapeutic potential of this newly identified JOSD2-LKB1 regulatory axis was then verified by both RNA interference and small-molecule inhibitors that abolish DUB activity of JOSD2 and exert potent anticancer activities.JOSD2 belongs to the MJD subfamily of DUB that also includes Ataxin-3, Atanxin-3L and JOSD1."