IndraLab

Statements

CD4 binds IL1B. 4 / 4
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"In xref and xref , it seems likely that IL-1β–expressing cells were associated with CD4 + cells, suggesting that the CD4 + cells might be involved, within the wall of the aneurysm, in activating IL-1β production in the dispersed macrophages and that, in turn, these cells might be activating the CD4 + cells, possibly through the presentation of autoantigens."
10637274
reach
"For Th17 polarizing conditions, CD4 + T cells were stimulated with plate bound anti-CD3 antibody (0.5 mug/ml) and anti-CD28 antibody (1 mug/ml) (BD Pharmingen), anti-IFN-gamma (2 mug/ml), anti-IL-4 (2[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
22819243
sparser
"Therefore, mPGES-1 stimulates an intercellular interaction between CD4 + T cells by upregulating the autocrine function of IL-1β in activated CD4 + T cells, which release IL-17 to facilitate axonal and myelin damage in EAE mice."
29257087
sparser
"Factors released from the interaction between IL-1β-competent myeloid cells and CD4 + T cells are highly toxic to neurons."
29358392