IndraLab

Statements

Bilirubin IXalpha inhibits IFNB1. 3 / 3

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"Bilirubin, but not SOD, blocked the cellular production of interferon-beta, while interleukin-6 production remained unaffected."

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"Nevertheless, our data clearly show that bilirubin disrupts TLR4 dependent Nox activation and interferon-beta production, which likely represents the molecular mechanism (s) underlying its inhibitory effect on iNOS expression in response to LPS."

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"Bilirubin also suppresses interferon-beta release via a ROS independent mechanism."

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INDRA sources:

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IndraLab

Statements

Bilirubin IXalpha inhibits IFNB1. 3 / 3

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