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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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USP18 inhibits cell differentiation. 3 / 3

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"USP18 depletion first stimulated differentiation initiation."

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"High levels of USP18 in murine hematopoietic cells block the cytokine induced terminal differentiation of monocytic cells (Liu et al., 1999)."

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"Deficiency of Usp18 reduced Th17 cell differentiation in vitro and in vivo as a result of hyperactivated NF-kappaB and NFAT signaling and increased levels of IL-2."

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Statements

USP18 inhibits cell differentiation. 3 / 3

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