IndraLab

Statements



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"USP18 depletion first stimulated differentiation initiation."

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"High levels of USP18 in murine hematopoietic cells block the cytokine induced terminal differentiation of monocytic cells (Liu et al., 1999)."

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"Deficiency of Usp18 reduced Th17 cell differentiation in vitro and in vivo as a result of hyperactivated NF-kappaB and NFAT signaling and increased levels of IL-2."