IndraLab

Statements

NEDD8 binds UCHL3. 12 / 13
5 1 | 3 3
biogrid
No evidence text available
16503656
biogrid
No evidence text available
14673145
sparser
"These observations suggest that UCH-L3 may function as a deneddylating enzyme 16 in vivo , although further studies are necessary to clarify whether UCH-L3 interacts with Nedd8 during spermatogenesis."
15466400
reach
"In vitro GST pull-down assay demonstrated that UCH-L3 bound to both NEDD8 and ubiquitin."
9790970
sparser
"18 These results suggest that Nedd8 may interact closely with UCH-L3 during testicular atrophy and germ cell loss."
15466400
sparser
"This study has proved UCHL3 regulated the ubiquitination NEDD8 level, suggesting NEDD8 may be a new substrate of deubiquitinase UCHL3, but the interaction between UCHL3 and NEDD8 as well as the effect of the deubiquitinating enzyme activity of UCHL3 on NEDD8 need to be confirmed [ xref ]."
40691601
reach
"While UCHL1 and UCHL3 both bind to NEDD8, the hydrolytic processing of NEDD8 is carried out by UCHL3 (Wada et al., 1998)."
35586714
reach
"UCH-L3, one of the ubiquitin C-terminal hydrolases, also binds to NEDD8 and functions as a NEDD8 C-terminal hydrolase (Wada et al., 1998)."
10806345
biogrid
No evidence text available
9790970
hprd
No evidence text available
9790970
biogrid
No evidence text available
9790970
biogrid
No evidence text available
9790970