IndraLab

Statements


5 1 | 3 2

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reach
"In vitro GST pull-down assay demonstrated that UCH-L3 bound to both NEDD8 and ubiquitin."

sparser
"18 These results suggest that Nedd8 may interact closely with UCH-L3 during testicular atrophy and germ cell loss."

reach
"While UCHL1 and UCHL3 both bind to NEDD8, the hydrolytic processing of NEDD8 is carried out by UCHL3 (Wada et al., 1998)."

reach
"UCH-L3, one of the ubiquitin C-terminal hydrolases, also binds to NEDD8 and functions as a NEDD8 C-terminal hydrolase (Wada et al., 1998)."

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sparser
"These observations suggest that UCH-L3 may function as a deneddylating enzyme 16 in vivo , although further studies are necessary to clarify whether UCH-L3 interacts with Nedd8 during spermatogenesis."

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No evidence text available

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No evidence text available