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Mutated ATXN3 inhibits DNA repair. 2 / 2

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"Expression of polyQ expanded mutant ATXN3 also decreases DNA repair efficiency and enhances vulnerability of cells following irradiation or exposure to genotoxins."

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"Insights into normal ATXN3 kinetics within the DDR could shed light on how mutant ATXN3 directly or indirectly disrupts DNA repair."

31669734

INDRA sources:

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IndraLab

Statements

Mutated ATXN3 inhibits DNA repair. 2 / 2

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