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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Mutated ATXN3 inhibits DNA repair. 2 / 2

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"Expression of polyQ expanded mutant ATXN3 also decreases DNA repair efficiency and enhances vulnerability of cells following irradiation or exposure to genotoxins."

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"Insights into normal ATXN3 kinetics within the DDR could shed light on how mutant ATXN3 directly or indirectly disrupts DNA repair."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...