IndraLab

Statements


OTUD6A activates Aurora-A. 5 / 5
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eidos
"Notably , OTUD6A promotes the protein half-life of Aurora-A and activates Aurora-A by increasing phosphorylation at threonine 288 of Aurora-A ."

reach
"OTUD6A Promotes Protein Stability and Kinase Activity of Aurora-A."

eidos
"Therefore , OTUD6A was selected as a DUB that binds to , deubiquitinates , and activates Aurora-A ."

eidos
"Consequently , our data suggest that Aurora-A , a critical mitotic regulator , is deubiquitinated , stabilized , and activated by OTUD6A , which in turn activates PLK1 to drive cells into mitosis ."

reach
"Notably, OTUD6A promotes the protein half-life of Aurora-A and activates Aurora-A by increasing phosphorylation at threonine 288 of Aurora-A."