IndraLab

Statements

TRAF6 binds USP3. 6 / 6
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sparser
"Since USP3 could inhibit IL-1β induced NF-κB activation, and TRAF6 polyubiquitination is critical in the process of IL-1β induced NF-κB activation [ 23 ], we further hypothesized that USP3 could inter[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
31056254
reach
"We provide the first evidence that USP3 binds directly to TRAF6 and inhibits TRAF6 induced NF-κB signaling pathway activation by ubiquitination in a DUB activity-dependent manner."
31056254
biogrid
No evidence text available
31056254
sparser
"We provide the first evidence that USP3 binds directly to TRAF6 and inhibits TRAF6 induced NF-κB signaling pathway activation by ubiquitination in a DUB activity-dependent manner."
31056254
sparser
"TRAF6 is a key E3 ubiquitin ligase that regulates the NF-κB signaling pathway, and our results prove that USP3 interacts with TRAF6 and regulates TRAF6 ubiuitination by DUB activity, but a variety of [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
31056254
sparser
"We found that USP3 interacted with TRAF6 and attenuated the polyubiquitination of TRAF6 induced by IL-1β, thereby negatively regulating NF-κB activation."
31056254