Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

COPS5 activates senp8. 2 / 2

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"The CSN deneddylase activity is catalyzed by the CSN5 subunit, in which the JAMM motif is the catalytic center required for the isopeptidase activity to remove NEDD8 from the cullin proteins XREF_BIBR, XREF_BIBR."

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"To what extend DenA and DEN1 supports or even substitutes the CsnE and CSN5 mediated deneddylase activity of the CSN complex needs to be resolved."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...