IndraLab

Statements

Capsaicin inhibits JUN. 3 / 5
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"Han et al. showed in a study published in 2002 that topical application of capsaicin on the skin of female ICR mice suppresses phorbol ester induced activation of nuclear factor kappaB (NF-kappaB) and activator protein 1 (AP-1) and concluded that this might be responsible for the chemopreventive effects of capsaicin [XREF_BIBR]."
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"Furthermore, capsaicin significantly reduced palmitate stimulated activation of c-Jun N-terminal kinase, c-Jun, and p38."
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"In fact, we found in this study that capsaicin inhibits c-jun induction, stimulated by MNNG, in the spleen, heart, stomach and lung."
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