IndraLab

Statements

Histone inhibits IFNB1. 2 / 2

| 2

reach

"In addition, Cigno et al. (2020) found that HPV E7 proteins from types 16 and 18 promote the expression of the histone methyl transferase SUV39H1, fostering the transcriptional repression of RIG-I, cGAS and STING, while the inhibition of SUV39H1 leads to the transcriptional activation of these genes and increased production of IFN-β and IFN-λ HPV [57]."

36428532

➶

reach

"Thus, IFN-β conditioning prior to infection decreases macrophage lactate production and histone lactylation."

39126652

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

Histone inhibits IFNB1. 2 / 2

INDRA sources:

Databases

Reading