IndraLab

Statements


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reach
"This possibility is bolstered by the observation of epistatic interactions between RNF216 and OTUD4, with simultaneous knockdown of both genes resulting in more severe phenotypes."

sparser
"Mutations in the ubiquitin ligase RNF216 and the deubiquitianse OTUD4 also associate with GHS."

sparser
"Indeed, the phenotype in the index pedigree appears to have been caused by the interaction of hypomorphic mutations in RNF216 and OTUD4 ."