IndraLab

Statements


USP18 increases the amount of EGFR. 2 / 2
| 2

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"In an RNA interference screen of 106 different genes related to deubiquitination, silencing of USP18 reduced EGFR expression without affecting the levels of other receptor tyrosine kinases [XREF_BIBR]."

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"We found that knockdown of Usp18 in several cell lines reduced expression levels of EGFR by 50-80%, whereas the levels of other receptor tyrosine kinases remained unchanged."