IndraLab

Statements

USP29 inhibits Neoplasms. 2 / 2
| 2
reach
"IHC analysis of Ki-67 and cleaved caspase-3 demonstrated strong inhibition of cell proliferation and massive intratumoral cell death in USP29-depleted tumors (Fig. 1H and I)."
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reach
"In our previous study, we revealed that USP29 promoted tumor cell aerobic glycolysis and glutamine anaplerosis by deubiquitinating and stabilizing the oncogenic MYC family and HIF1α, and systemic knockout of USP29 significantly suppressed tumor progression and prolonged the survival of tumor-bearing mice."
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