IndraLab

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BRAF-G469A activates phosphorylated ERK. 1 / 1
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reach
"Inductions of the expression of BRAF V600E, V600K, K601E, L597Q, G469A, G469V, or G464V at levels comparable to those of endogenous BRAF caused significant induction of p-MEK and p-ERK and marked inhibition of RAS-GTP and pCRAF S338."