IndraLab

Statements

OTUD1 binds NFE2L2. 4 / 4
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"Our findings demonstrated that the interaction between OTUD1 and NRF2 primarily occurred through its Neh2 domain (aa 1–111), as the Neh2 deletion truncation (NRF2-E) failed to bind with OTUD1 in HEK293T cells ( xref D)."
39079388
sparser
"Collectively, these results suggest a physical interaction between OTUD1 and NRF2."
39079388
reach
"Our findings demonstrated that the interaction between OTUD1 and NRF2 primarily occurred through its Neh2 domain (aa 1–111), as the Neh2 deletion truncation (NRF2-E) failed to bind with OTUD1 in HEK293T cells (Fig. 5D)."
39079388
reach
"Our mass spectrometric analysis reveals that OTUD1 binds KEAP1, a regulator of the transcription factor Nrf2, during ROS-induced oxidative stress [19] (Figure 5C)."
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