IndraLab

Statements


USP9X deubiquitinates STMN1. 3 / 3
1 | 2

reach
"However, whereas USP9X deubiquitinates wild-type SMN protein, its mutated form is unaffected by USP9X, causing its rapid degradation, and thereby contributes to impaired neuronal growth and development [27]."

reach
"Studies have shown that USP9X regulates protein transport, cell migration, and cell adhesion by deubiquitinating NUAK1, MARCH, MCL-1, mTOR, SMN, Bcl 10, and PEX5 to participate in crucial pathophysiol[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

"In this report, we find that <span class="match term0">Usp9x</span>, a deubiquitinating enzyme, stably associates with the <span class="match term1">SMN</span> complex via directly interacting with <span class="match term1">SMN</span>."