IndraLab

Statements


CLSPN activates USP20. 1 / 1
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reach
"Nevertheless, in USP20 knockdown cells, reconstitution of Claspin was able to rescue phospho-CHK1 levels and significantly suppress tumorigenesis, even if Rad17 levels was decreased, suggesting that Claspin is an important target of USP20 in mediating checkpoint activation and tumor suppression."