IndraLab

Statements

SIRT1 inhibits ATXN3. 3 / 3
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"SIRT1 overexpression decreases MJD neuroinflammation."
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"Furthermore, the pharmacological activation of SIRT1 with resveratrol significantly reduces motor incoordination of MJD mice."
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"The results show that SIRT1 overexpression significantly reduced the characteristic MJD neuropathology highlighting the role and importance of SIRT1 in the disease."
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