IndraLab

Statements

MED1 binds BAP1. 6 / 6
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"Med1 is associated with BAP1."
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"To investigate the interaction between Med1 and BAP1 protein, co-immunoprecipitation was performed in the BAP1 overexpressing cell line, BAP1 WT and BAP1 C91A mutant were overexpressed, and IP was performed using an anti-Med1 antibody in BAP1 or BAP1 C91A overexpressed cells."
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"These results demonstrate that BAP1 is associated with Med1, but not with the BAP1 catalytic mutant."
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"In addition, an examination of the interaction between Med1 and BAP1 proteins showed that Med1 and BAP1 proteins are binding and are involved in the development and metastasis of cancer ( xref )."
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"Although the binding of Med1 and BAP1 involved in the cancer growth or metastasis, mechanisms are still unclear."
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"However, in the future, the results of this study will contribute to various research fields, such as the mechanism of regulating the expression of target genes by the binding of Med1 and BAP1 and the growth and metastasis of cancer by Med1 and BAP1."
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