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Valproic acid inhibits NFKBIA. 2 / 2

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"In this study, down-regulation of IkappaBalpha by VPA mediated the activation of NF-kappaB as evidenced by increased translocation of p65 and p50 to nucleus."

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"Thereby, VPA could prolong the prostratin induced IkappaBalpha degradation by prolonging the IKK activity, as we have previously shown for the TNFalpha+ TSA combined treatment XREF_BIBR."

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Statements

Valproic acid inhibits NFKBIA. 2 / 2

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