
IndraLab
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"The gpc4 is required for C&E of both the mesoderm and endoderm and interacts with wnt11f2 . xref The gpc4 zebrafish mutants present broader and shorter body axis, the mutation is lethal after 5–7 dpf, but rescue experiments revealed that gpc4 has a role in regulating cartilage cell polarity, chondrocyte stacking, and endochondral ossification. xref "