IndraLab

Statements

USP8 activates Wnt. 4 / 4
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"Thus, our study demonstrated that USP8 activated the Wnt/beta-catenin signaling through a post-translational mechanism of β-catenin."
37311739
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"USP8 and UBPY is reported to activate the Wnt and beta-catenin pathway by targeting Frizzled G protein coupled protein XREF_BIBR."
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"USP8 enhances Wnt signaling through deubiquitinating FZD5 ."
36340031
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"Additionally, the deubiquitinating enzymes UBPY and USP6 may promote the recycling of endocytosed FZD back to the surface and restore Wnt signaling."
29632210