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USP12 deubiquitinates Histone-H2A. 3 / 3
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"It was shown that USP12 deubiquitinates histones H2A and H2B both in vitro and in vivo [3] ."

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"USP12 and USP46 can deubiquitinate histones H2A and H2B, thereby playing a critical role in Xenopus development [91] ."

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"Joo et al. demonstrated that USP46 and USP12 containing fractions from HeLa cells can deubiquitinate histones H2A and H2B to control cell fate and gastrulation during Xenopus development [XREF_BIBR]."