IndraLab

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USP18 binds IFNLR1. 4 / 4
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"However, the performed co-immunoprecipitation experiments did not suggest direct interaction of USP18 with IL-28R1 (Supporting Information xref )."
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"Indeed, preliminary data from our laboratory show that USP18 can bind to type III IFN receptor IL-28RA, and has no inhibitory effect on type III IFN signaling in U6A cells (Arimoto et al. unpublished data)."
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"Indeed, preliminary data from our laboratory show that USP18 can bind to type III IFN receptor IL-28RA, and has no inhibitory effect on type III IFN signaling in U6A cells (Arimoto et al. unpublished data)."
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"Since we have shown that binding of Usp18 to type I IFN receptor subunit 2 (Ifnar2) is important for Usp18 mediated downregulation of type I IFN signalling (Malakhova et al, xref ), we investigated a potential interaction of Usp18 with the IFN-λ specific receptor subunit IL-28R1."
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