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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP10 activates CDKN1A. 2 / 3

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"As shown in XREF_FIG, overexpression of WT USP10 increased p21 promoter activity in HCT116 p53 +/+ cells, but not in HCT116 p53 -/- cells."

20096447

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"Stable knockdown of USP10 by shRNA inhibited p21 promoter activity in HCT116 p53 +/+ cells, but had little effect in HCT116 p53 -/- cells (XREF_FIG)."

20096447

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...