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UCHL3 deubiquitinates POLD4. 5 / 5
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"UCHL3 induces radiation resistance and acquisition of mesenchymal phenotypes by deubiquitinating POLD4 in glioma stem cells."
38829550
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"In view of the essential role of the enzyme activity of UCHL3 in driving POLD4 stabilization, we proposed that UCHL3 may deubiquitylate POLD4."
38829550
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"In MES GSCs, knockdown of UCHL3 increased the levels of POLD4 ubiquitination (Fig. 5J)."
38829550
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"Based on a DUB-siRNA profiling screen, UCHL3, as a unique DUB of POLD4, was confirmed to bind directly to, stabilizes, and deubiquitinates POLD4 in GSCs."
38829550
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"It has been shown that UCHL3 induces radiation resistance and the acquisition of mesenchymal phenotypes by deubiquitinating p12 in glioma stem cells."
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