IndraLab

Statements

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"The MAPK p38-alpha (MAPK14) was also downregulated by LPS in cluster 1."
19285553
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"In addition, UFH inhibited the LPS induced activation of mitogen activated protein kinase 14, proto-oncogene tyrosine protein kinase Src and nuclear factor kappaB signaling in HUVECs."
29285085
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"Furthermore, pretreatment with ISO also resulted in a reduction of LPS-stimulated inflammation signaling markers, Mapk14 and NF-kappaB, in human THP-1 cells."
38129360
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"siRNA knockdown of MAPK14 and MAPK12, which encode p38-alpha and -gamma respectively, inhibited TNF-alpha production by LPS stimulated macrophages (MAPK14, 31.80 +/- 19.52 SEM%; MAPK12, 21.78 +/- 15.64 SEM%) as did knockdown of SYK (22.50 +/- 16.20 SEM%), but inhibition never exceeded 50%."
25891413