IndraLab
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"Consistent with our previous study [XREF_BIBR], the inhibitory function of CYLD on NF-kappaB relies on its intact catalytic activity because expression of a catalytically inactive CYLD C601A mutant, in which cysteine601 is substituted by alanine, could not enhance the abundance of IkappaBalpha to the equivalent extent as wild-type CYLD did (XREF_SUPPLEMENTARY)."