IndraLab

Statements

Pimozide activates USP1. 3 / 3
| 3
reach
"The most potent inhibitors, pimozide and GW7647, inhibited USP1 and UAF1 reversibly with a micromolar IC 50."
23797609
reach
"The top inhibitors, pimozide and GW7647, blocked USP1 and UAF1 noncompetitively with a Ki of 0.5 and 0.7 muM, respectively, and displayed selectivity against a number of deubiquitinases, deSUMOylase, [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
29958636
reach
"The top inhibitors, pimozide and GW7647, inhibited USP1 and UAF1 noncompetitively with a K i of 0.5 and 0.7 muM respectively, and displayed selectivity against a number of deubiquitinases, deSUMOylase and cysteine proteases."
22118673