IndraLab

Statements

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"Our experiments further confirmed that USP5 knockdown could suppress ovarian cell proliferation both in vitro and in vivo."
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"Down-regulation of USP5 inhibited cell proliferation of ovarian cancer cells."
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"In contrast, genetic or chemical inhibition of USP5 leads to CCND1 degradation, thereby resulting in decreased NSCLC cell proliferation and tumor growth."
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"As shown in Figure 3B, NC had little effect on USP5 expression compared to the Control group, and USP5 shRNAs (#1, #2 and #4) reduced USP5 protein expression in both cell lines.Following USP5 shRNAs (#1 and #2) transduction, the proliferation of both cancer cell lines was determined using CCK-8 assays, which showed that down-regulation of USP5 caused profoundly reduced proliferation of both ovarian cancer cell lines (Figure 3C, P<0.001)."
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"The siRNA-induced knockdown of Usp5 inhibited cell proliferation, migration ability and drug resistance."
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