IndraLab

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Genome polyprotein increases the amount of KCNMA1. 3 / 3
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"In conclusion, E2 at physiological concentrations augments K (Ca) currents through ERbeta in the GT1-7 GnRH neuronal cell line and increases the expression of the BK channel subunit mRNAs, alpha and beta4."
17962348
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"Not only does E2 increase the mRNA expression of Kcnma1 (Figure 8G), but also the maximum BK (IbTx-sensitive) current by 3-fold, which would facilitate rapid repolarization during burst firing and promote glutamate release similar to hippocampal CA1 neurons.In contrast to BK channel expression, E2 did not affect the mRNA expression of SK3 channel mRNA."
38915596
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"E2 treatment significantly increased the mRNA expression of the BKα1 (Kcnma1) subunit."
38915596