IndraLab

Statements

TCR increases the amount of TNFAIP3. 2 / 2
| 1 1
reach
"Ligation of the TCR has been shown to induce TNFAIP3 expression 21 and corticosteroids are commonly used as treatment for MOG-AAD which can aid in the resolution of relapses and potentially prevent new relapses XREF_BIBR, XREF_BIBR."
32709905
sparser
"However, mutating the O-GlcNAcylation site of c-Rel or treating cells with PUGNAc has no effect on TCR or TNF-α induced expression of TNFAIP3 (encodes TNF-α induced protein 3) and NFKBIA (encodes NF-κB inhibitor α), genes that are considered to contain c-Rel binding sites in their promoters ( xref )."
31198979